Single dose vaccine, Sputnik Light, authorized for use in Russia

07/05/2021 13:04

Single dose vaccine, Sputnik Light, authorized for use in Russia


The Russian Ministry of Health, the Gamaleya National Research Center of Epidemiology and Microbiology and the Russian Direct Investment Fund (RDIF, Russia’s sovereign wealth fund) announce that Sputnik Light, a single dose COVID-19 vaccine, has received authorization for use in Russia.

Sputnik Light is the first component (recombinant human adenovirus serotype number 26 (rAd26)) of the Sputnik V coronavirus vaccine.
The single dose Sputnik Light vaccine demonstrated 79.4% efficacy according to analyzed data taken from 28 days after the injection was administered. An efficacy level of near 80% is higher than that of many two-dose vaccines.

The efficacy rate was calculated based on data obtained from Russians vaccinated with a single injection, having not received the second one for any reason during the mass vaccination program between December 5, 2020 and April 15, 2021.

The infection rate among vaccinated subjects from the 28th day from the date of the injection was only 0.277%. Over the same period, the infection rate among the unvaccinated adult population was 1.349%.

Phase I/II Safety and Immunogenicity Study of the single dose Sputnik Light vaccine was initiated in January 2021, and the interim results were received on March 10, 2021:

• The results demonstrated that the vaccine can elicit the development of antigen specific IgG antibodies in 96.9% of volunteers on the 28th day after immunization;
• Virus-neutralizing antibodies developed in 91.67% of volunteers on the 28th day post immunization.
• Cellular immune response against the S Protein of SARS-CoV-2 developed in 100% of volunteers;
• No serious adverse events were registered after vaccination with Sputnik Light;
• The immunization of individuals with pre-existing immunity against SARS-CoV-2 with Sputnik Light can elicit an increase of the level of IgG antibodies by more than 40x in 100% of volunteers on the 10th day after immunization;
• Sputnik Light demonstrated safety for all subjects, including those with pre-existing immunity to SARS-CoV-2.

On February 21, 2021 the Gamaleya Center and RDIF launched a global efficacy study of Sputnik Light. The Phase III clinical study involving 7,000 people is conducted in multiple countries including Russia, the UAE, Ghana and others. The interim results are expected in May 2021.

As of May 5, 2021, more than 20 million people globally have received the first injection of the Sputnik V vaccine, containing the first component. There have been no cases of Cerebral Venous Sinus Thrombosis (CVST) reported. The production of the vaccine meets the strictest standards, with four stages of purification (two chromatographic stages and two stages of tangential filtration).

The Sputnik Light vaccine is based on a well-studied human adenoviral vector platform that has proven to be safe and effective. The cost of the Sputnik Light vaccine globally will be less than $10, while it has simple storage requirements, at +2 +8, which provide for easy logistics. The one shot regimen allows for the vaccination of large groups of the population in a short time, helping to speed up the fight against the pandemic during the acute phase.


In case you have found a mistake in the text, please send a message to the editor by selecting the mistake and pressing Ctrl-Enter.

Newsfeed

23/06/2021 16:50 Deployment of border guards possible only after Azeri forces leave Armenia's sovereign territory – acting vice PM 23/06/2021 15:54 India ranks second after US with over 30 mln COVID-19 cases 23/06/2021 15:02 Process on return of detainees continues – Armenia acting vice PM 23/06/2021 14:56 Geopolitical processes becoming increasingly turbulent — Putin 23/06/2021 14:12 Russia reports over 17,500 daily COVID-19 cases — crisis center 23/06/2021 13:49 One more family left the dilapidated metal container 23/06/2021 13:32 Vanetsyan – Our attitude to Pashinyan to be mirror-like 23/06/2021 12:49 All made mistakes this is why today we have such results: Artur Vanetsyan 23/06/2021 12:40 Artur Vanetsyan says he will be in legislature if bloc decides to accept the mandates 23/06/2021 12:00 Global COVID-19 case count down 6% in past week — WHO 23/06/2021 11:17 Armenia documents 100 new coronavirus cases in 24 hours, one death recorded 23/06/2021 10:57 Odzun community head beaten in Lori governor's office for supporting Kocharyan in elections: Armenian Human Rights Defender’s office to send letter to Attorney General's Office 22/06/2021 21:26 "Armenia" bloc says political pressures launched against its supporters 22/06/2021 17:24 Armenia President holds phone conversation with "I Have the Honor" bloc candidate Artur Vanetsyan 22/06/2021 17:13 Cooperation and security without dividing lines is a common goal of countries — Putin 22/06/2021 16:17 Body of serviceman found in Varanda region 22/06/2021 15:48 Ruling force, its head have no idea of Armenia’s development – political technologist 22/06/2021 15:09 Sputnik V effective against Indian strain, Russian expert says 22/06/2021 14:26 Russia reports 16,715 daily coronavirus cases — crisis center 22/06/2021 13:55 Russia to continue cooperating with newly elected Armenian parliament: Russian Federal Council Speaker 22/06/2021 13:04 If authorities continue in the same way, Armenia will face another early elections – Kocharyan 22/06/2021 12:53 Five new cases of coronavirus reported in Artsakh 22/06/2021 12:38 Armenia bloc to continue struggling for power, is not coming just for mandates – Kocharyan 22/06/2021 12:25 Pashinyan's words aimed to show something to external world: Kocharyan on Pashinyan's reconciliation statement 22/06/2021 12:07 No final decision about parliamentary mandates made yet – Kocharyan on taking the seats in the new parliament 22/06/2021 11:58 Armenia documents 77 new coronavirus cases in 24 hours, four eaths recorded 22/06/2021 11:57 This is the last bullet of the revolution – Kocharyan on election results 22/06/2021 11:35 Armenia excludes any concessions in its territory – Artak Davtyan 22/06/2021 11:22 Russia's ambassador says transfer of 15 detainees became possible due to Russia's preparatory works 22/06/2021 10:57 Negotiations ongoing with Russia to deploy Russian border guards on Armenian-Azerbaijani border – Chief of General Staff 22/06/2021 10:27 The United States is committed to strengthening our partnership with Armenia: The USA congratulates the people of Armenia on June 20 parliamentary elections 21/06/2021 19:21 "I Have the Honor" bloc says it will continue the fight 21/06/2021 17:50 PAP refrains from assessing election results, will voice its position after investigation of election frauds 21/06/2021 17:02 Armenia bloc to use entire toolkit to dispute results of elections, to start consultations with other forces 21/06/2021 16:41 Moscow to wait for formation of government in Armenia: Lavrov 21/06/2021 16:33 Seven countries side with EU decision to close skies for Belarusian airlines — EU Council 21/06/2021 15:53 Kocharyan's "Armenia" bloc does not accept election results, to apply to CC 21/06/2021 15:45 International observers positively assess organization and conduction of early parliamentary elections in Armenia 21/06/2021 14:56 Russia documents 17,378 COVID-19 cases in 24 hours 21/06/2021 14:08 Kremlin sees landslide victory belongs to Pashinyan's party - Peskov 21/06/2021 13:14 Rejection of mandates by "Armenia" and "I Have the Honor" blocs the only way to remove Pashinyan – attorney 21/06/2021 13:01 Mandates distributed among parties set to receive them by Electoral Code – CEC chairman 21/06/2021 12:35 Three people wounded in shooting in Berlin 21/06/2021 12:01 Pashinyan’s Civil Contract party to have 71 seats out of 105 in the new parliament 21/06/2021 11:52 CIS observers assess elections in Armenia as open, fair and objective 21/06/2021 11:09 Armenia documents 26 new coronavirus cases in 24 hours, one death recorded 21/06/2021 09:46 Civil Contract to have constitutional majority and form Armenia's cabinet – Pashinyan 21/06/2021 08:30 Forces headed by Pashinyan, Kocharyan and Vanetsyan to form new parliament in Armenia 21/06/2021 06:26 "Armenia" bloc does not accept election results 21/06/2021 06:10 What was predicted happened – Armenia's citizen made the decision: Nikol Pashinyan 20/06/2021 21:17 Voter turnout at Armenia's parliamentary polls reaches 49,4% as of 8pm 20/06/2021 18:21 Voter turnout in snap parliamentary elections in Armenia 38,17% as of 5pm - CEC 20/06/2021 17:30 "I Have the Honor" bloc representative voices about violations in provinces 20/06/2021 17:11 Defeated authorities grasp at any straw – “I Have the Honor” headquarter representative 20/06/2021 16:22 Sputnik V protects against all known coronavirus strains, developer says 20/06/2021 15:13 Voter turnout in snap parliamentary elections in Armenia 26.82% as of 2pm - CEC 20/06/2021 13:52 Armenian Catholicos casts his ballot 20/06/2021 13:44 Armenia’s third president says he voted for secure, sovereign economically developed Armenia 20/06/2021 12:40 "Armenia" bloc member Vahe Hakobyan does not exclude provocations by authorities from despair 20/06/2021 12:22 12,20% of voters cast their ballots by 11am – Armenia CEC 20/06/2021 12:10 Police officers use force, apprehend head of "Armenia" bloc headquarters in Parakar community (video) 20/06/2021 12:03 "I Have the Honor" bloc candidate votes for future of Armenia and Artsakh 20/06/2021 11:51 Police prepare materials on anti-propaganda materials spread in Yerevan streets against "Armenia" bloc 20/06/2021 11:02 Armenia’s second president says he voted for dignified peace and economic rise 20/06/2021 10:29 "Armenia" bloc applies to Police, demands apprehending masterminds, disseminators of materials containing hatred, insult 20/06/2021 09:52 Search conducted in Armenia bloc’s chief headquarter in Sisian 20/06/2021 09:49 Brazil hits 500,000 covid deaths amid 'critical' situation 20/06/2021 09:16 Izmirlyan Medical Center director released 19/06/2021 15:25 Armenia president holds phone conversation with NSS, Police chiefs ahead of snap elections tomorrow 19/06/2021 15:16 Artur Vanetsyan says terror launched from early morning against "I Have the Honor" team, members summoned and taken to Police, NSS, SIS 19/06/2021 14:26 Ebrahim Raisi wins Iran’s presidential election 19/06/2021 12:42 Armenia documents 81 new coronavirus cases in 24 hours, 4 deaths recorded 19/06/2021 12:39 Two new cases of coronavirus reported in Artsakh 19/06/2021 12:09 One person dead, 1,500 people evacuated, 300 houses flooded in Crimea due to heavy rains 19/06/2021 11:34 Today is the day of silence in Armenia – no agitation allowed 19/06/2021 11:21 Vote fairly and freely, according to your conscience only: Armenia President 18/06/2021 20:58 Give us opportunity to advance the country in all directions – Robert Kocharyan to supporters 18/06/2021 20:46 Armenia bloc ARF-D member says no transactions to be carried out behind people’s backs 18/06/2021 20:39 Two days remained to our victory – Armenia bloc conducts rally in Republic Square 18/06/2021 20:33 Director of Izmirlyan Medical Center, member of Armenia bloc arrested 18/06/2021 15:54 Russia keeps a close eye on information Turkey may create military base in Azerbaijan 18/06/2021 14:50 Russia records 17,262 new daily COVID-19 cases, the highest number since Feb 1 18/06/2021 14:02 Russia in close contact with Azerbaijan, Armenia, Turkey on Nagorno-Karabakh 18/06/2021 13:05 "Armenia" bloc – 28,7%, Civil Contract 25,2% - Gallup publishes poll results 18/06/2021 12:50 Armenia's foreign policy and diplomacy totally ruined – expert 18/06/2021 12:08 Two new cases of coronavirus reported in Artsakh 18/06/2021 11:38 North Korea should be ready for both dialogue and standoff with US — Kim Jong-un 18/06/2021 11:01 Armenia documents 86 new coronavirus cases in 24 hours, one death recorded 18/06/2021 10:46 Delimitation, demarcation issues should not be discussed only from the political and military viewpoints – Armenia Ombudsman 17/06/2021 19:34 People brought to Nikol Pashinyan's rally from provinces by buses 17/06/2021 17:03 Kim Jong-un admits North Korea facing a 'tense' food shortage 17/06/2021 16:16 Diana Ross reveals first album in 15 years, Thank You (video) 17/06/2021 15:22 Russia documents over 14,000 COVID-19 cases in past 24 hours 17/06/2021 14:37 Biden and Putin praise Geneva summit talks but discord remains 17/06/2021 14:06 Botswana diamond could be world's third largest 17/06/2021 13:44 Child, 14, seriously injured as a result of traffic accident with involvement of acting minister’s car in Armenia 17/06/2021 13:33 Magnitude-2.7 earthquake reported in Armenia’s Vayots Dzor 17/06/2021 13:11 China space station: First crew arrives on Shenzhou-12 17/06/2021 12:49 US lost as much as Russia due to sanctions — Putin 17/06/2021 12:10 Number of missing servicemen as of this moment stands at 275 – Acting PM’s aide